NMP

Competitive manufacturing industry must be able to react to change and to understand the balance of possible options when making decisions on complex multi-faceted problems. Understanding how best to configure and re-configure a global production network, set against rapidly changing product-service requirements is one such complex problem area. This project aims to provide services that support the design and provision of flexible interoperable networks of production systems that can rapidly and accurately be re-configured.

The main objective of this research proposal is to identify and elaborate those characteristics of ENM that determine their biological hazard potential. This potential includes the ability of ENM to induce damage at the cellular, tissue, or organism levels by interacting with cellular structures leading to impairment of key cellular functions. These adverse effects may be mediated by ENM-induced alterations in gene expression and translation, but may involve also epigenetic transformation of genetic functions.

CosmoPHOS-nano is a multidisciplinary, translational and business-oriented project, aiming to accomplish the following objectives:
1) Develop the CosmoPHOS system, which is a novel theranostic (diagnostic & therapeutic) nanotechnology-enabled portable combination system enabling endovascular in vivo near-infrared fluorescence molecular imaging, endovascular near-infrared targeted photodynamic therapy, real-time & follow-up therapy monitoring of atherosclerotic coronary artery disease (CAD),
2) Nonclinically evaluate this system,

The NanoMILE project is conceived and led by an international elite of scientists from the EU and US with the aim to establish a fundamental understanding of the mechanisms of nanomaterial interactions with living systems and the environment, and uniquely to do so across the entire life cycle of nanomaterials and in a wide range of target species. Identification of critical properties (physico-chemical descriptors) that confer the ability to induce harm in biological systems is key to allowing these features to be avoided in nanomaterial production (safety by design).

The suggested project aims at developing a nanowire (NW) technology applied to III-nitride and III-V materials to improve the present Solid State Lighting (SSL) solutions. Present white light emitting diode (LED) emitters are based on thin film III-nitride technology, and a combination of violet-blue LEDs and suitable phosphor coatings has yielded a light emission efficacy of > 100 lm/W with an operating lifetime > 50000 hrs in commercial white LEDs. The colour rendering is generally unsatisfactory, however, and the cost is so far prohibitive for general market penetration.

Manufacturated nanomaterials and nanocomposites are being considered for various uses in the construction industry and related infrastructure industries, not only for enhancing material properties and functions but also in the context of energy conservation. Despite the current relatively high cost of nano-enabled products, their use in construction materials is likely to increase because of highly valuable properties imparted at relatively low additive ratios, rapid development of new applications and decreasing cost of base MNMs as they are produced in larger quantities.

This proposal aims at developing a new generation of novel materials for high performance permanent magnets (PM) with energy product 60 kJ/m3 <(BH)max < 160 kJ/m3, which do not contain any rare-earths or platinum. To achieve this objective two strategies will be used: a) exploitation of shape anisotropy of high magnetic moment materials produced in the form of high-aspect-ratio (>5) nanostructures by environmentally friendly synthesis methods and b) using high-throughput (HT) thin film synthesis and characterization techniques to identify new PM candidate phases.

ModNano-Tox will develop a number of well-documented and technically advanced models describing the behaviour of engineered nano-particles in organisms and the environment. Background to these models will be a thoroughly documented database, constructed based on: (1) an advanced evaluation of physicochemical properties of nano-particles and in silico modelling of their reactivity; and (2) assessment of the characterisation methodologies as well as toxicity protocols used to develop biological responses in toxicological studies.

The NanoCom coordinated action will contribute to bridging the gap between lab based and industrial applications in nanotechnology by creating a European wide approach and mechanisms for lowering the barriers and spreading best open innovation practices for rapid commercialisation and investment in innovative nanotechnology driven products.