Alpha-Catenin regulatory properties and functions during Zebrafish development.

Adherens junctions (AJ) play key roles in cell-cell adhesion, cell migration and cell signaling in a variety of biological processes. AJ are dynamic structures composed of cell-cell adhesion proteins (cadherin super-family), associated adaptor proteins (alpha-, and beta-catenin) and other proteins (p120) that locally regulate the actin cytoskeleton. The functions of two components of the AJ, cadherins and beta-catenin, are well understood, but the function of alpha-catenin is not.

Short name and number: 
Alpha-Catenin roles (236027)
Name of US Partner: 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Contact: 

EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) / REINKE Genevieve

Participating Countries: 
United States
Area: 

No theme specific

Category: 

FP7 Project with U.S. partner