Allelic Exclusion of Antibody Gene Expression
Antibody genes in B lymphocytes are assembled from multiple rearranging gene segments, enabling the immune system to protect us from a huge diversity of pathogens. Each B lymphocyte expresses only one antibody specificity on the cell surface (monospecificity), even though there is more than one allele for each antibody chain, a phenomenon termed allelic exclusion.
Short name and number:
Kappa Flex Mouse (235297)
Name of US Partner:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Contact:
FRIEDRICH-ALEXANDER UNIVERSITAET ERLANGEN-NUERNBERG (DE) / WINDERL Ulrich
Participating Countries:
United States
Area:
Health
Category:
FP7 Project with U.S. partner
